The Effect of PVP Viscosity on the Binding Performance in Naproxen Tablets

Certain active ingredients can present flow and compactability challenges, requiring wet granulation to enable high-speed tableting. This study compares the performance of VIVAPHARM^® PVP K25, VIVAPHARM^® PVP K30, and VIVAPHARM^® PVP K90, respectively, as wet-granulation binders in an immediate-release formulation of naproxen as the model API.