29. Jan 2016
Roller compaction, or dry granulation, is a manufacturing method for pharmaceutical and nutraceutical tablets that continues to gain importance. In order to achieve the desired granule properties, it is vital to use efficient binder-filler systems, which enable easy compaction, reproducible milling results, and high re-compactibility during the final tableting step. This study examines the effect of silicification on the roller compaction performance of microcrystalline cellulose.