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VIVAPHARM® PVPP

VIVAPHARM® PVPP

Crospovidone

Unsurpassed Disintegratioin

VIVAPHARM® PVPP, Crospovidone, is unsurpassed in its performance and versatility as a superdisintegrant in formulations.

It combines different mechanisms to achieve rapid tablet disintegration at low concentrations (1-5%). Due to its viscoelasticity, VIVAPHARM® PVPP is highly compactable, resulting in robust tablets with increased tensile strength and reduced friability. Scanning electron microscope images of VIVPHARM® PVPP show a granular and porous structure with a large surface area. It enhances the dissolution of poorly soluble drug actives and due to its non-ionic property, it does not bear any risk of interaction with cationic APIs.

VIVAPHARM® PVPP is available in two particle sizes to serve different application requirements.

Benefits of Using VIVAPHARM® PVPP

  • Rapid disintegration at low concentrations (1-5%)
  • Functions via a combination of disintegration mechanisms (wicking, shape recovery, and swelling), thus imparting its unsurpassed versatility as a superdisintegrant in formulations
  • Suitability for use in direct compression, wet granulation, and dry granulation
  • Increased tablet tensile strength and reduced friability due to high compressibility
  • No gel formation even at higher concentrations (10%) – ideal for ODTs
  • VIVAPHARM® PVPP

    Crospovidone, Ph.Eur, USP/NF, JP, E 1202, FCC

    Grade

    Chemical Name

    Average Particle Size by
    Laser Diffraction [µm]

    Compendial Type

    VIVAPHARM® PVPP XL


    Polyvinylpyrrolidone,
    crosslinked

    125

    A

    VIVAPHARM® PVPP XL-10

    30

    B

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