VIVAPHARM® PVP/VA
VIVAPHARM® PVP/VA

VIVAPHARM® PVP/VA

Copovidone

Ultimate Binder for Tablets

VIVAPHARM® PVP/VA 64 is a 6:4 linear random copolymer of N-vinylpyrrolidone and vinyl acetate. The vinyl acetate component of VIVAPHARM® PVP/VA 64 reduces the hydrophilicity and glass transition temperature (T g ) compared to povidone homopolymers of similar molecular weight.

As a result, VIVAPHARM® PVP/VA 64 is the ultimate tablet binder that extends its excellent adhesive property in wet granulation, as well as in dry granulation and direct compression.

Due to its spherical, hollow particle morphology and high plasticity, VIVAPHARM® PVP/VA 64 performs exceptionally well as a binder for direct compression.

In addition, a lower T g makes VIVAPHARM® PVP/VA 64 an ideal polymer matrix for solid dispersions/solutions via hot melt extrusion, which enhances the dissolution of poorly soluble drug actives.

Benefits of Using VIVAPHARM® PVP/VA

  • Suitability for use in direct compression, dry granulation, wet granulation, hot melt extrusion, and film coating.
  • Good flowability
  • Large surface area due to hollow particle morphology – enhances particle bonding and good compressibility
  • Ideal glass transition temperature (T g ) for hot melt extrusion
  • Get your free sample now
    Get your free sample now

    Get Your Free Sample Now!

    Privacy Policy

    We Value Your Privacy This website uses external tools and components to provide you the best experience on our website. You will find more detailed information in our privacy policy and imprint.