Orally Disintegrating Tablet Excipient Matrix Microcrystalline Cellulose, Colloidal Silicon Dioxide, Mannitol, Fructose, Crospovidone

PROSOLV® ODT G2 is a high functionality excipient for orally disintegrating tablet formulation, development, and manufacture. This innovative orally disintegrating tablet (ODT) matrix is a unique combination of soluble and insoluble ingredients manufactured using JRS Pharma's co-processing technology.

It provides a pleasing, convenient, and discreet form of administration for active pharmaceutical and nutritional ingredients without the need for water. PROSOLV® ODT G2 offers the functional performance needed for today's orally disintegrating tablet formulation challenges and complies with globally accepted and monographed raw materials.

PROSOLV® ODT G2 addresses formulation and manufacturing challenges with a robust functional performance that high-speed tablet manufacturing requires. Patients experience tablets with pleasing mouth-feel and fast disintegration in the oral cavity, with no need for water.


  • Smooth and creamy mouthfeel
  • Excellent flowability
  • Superior compaction profile when compared to other matrices
  • Excellent blending characteristics for improved content uniformity
  • High patient compliance

ODT Excipient Matrix
License and Royalty Free



Average Particle Size by Laser Diffraction (µm)

Bulk Density (g/mL)

Main Application


Microcrystalline Cellulose,
Colloidal Silicon Dioxide,


0.45 – 0.65

PROSOLV® ODT G2 is a simple-to-use co-processed composite derived from JRS PHARMA’s patented PROSOLV® Technology. Its primary application is for the development and manufacture of orally disintegrating tablets allowing the discrete and convenient administering of medicines without water for high patient compliance.

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