VIVAPUR® & EMCOCEL®
Microcrystalline Cellulose
Microcrystalline cellulose (MCC) is an odorless, tasteless, porous white powder derived from pharmaceutical grade wood pulp. With a wide range of chemical, technical, and economic benefits, MCC is one of the most widely used binder excipients for tablet formulations.
VIVAPUR® & EMCOCEL® offer:
- High compactibility
- Robust tablets with low friability
- High production yields
- Cost savings due to reduction in dosage levels
- Compatibility with most APIs (inert)
Microcrystalline Cellulose, Ph. Eur., NF, JP, E 460(i), FCC | |||||
Type | Type | Average Particle Size by Laser Diffraction (µm) | Bulk Density (g/mL) | Main Application | |
VIVAPUR® | EMCOCEL® | ||||
VIVAPUR® 105 |
| 15 | max 0.26 |
| Very fine grade, which gives a pleasant mouth feeling, masks bitter tastes and supports flavors. |
VIVAPUR® 101 | EMCOCEL® 50 M | 65 | 0.26 – 0.31 | 0.25 – 0.37 | Fine standard MCC grade, especially suited for wet granulation, roller compaction and spheronization. Very high compactibility. |
VIVAPUR® 103 |
| 65 | 0.26 – 0.31 |
| Same quality as grade 101/50M, but very low moisture content (< 1.5 %) for processing water-sensitive actives. |
VIVAPUR® 301 |
| 65 | 0.35 – 0.46 |
| Same quality as grade 101, but increased bulk density and improved flow properties. |
VIVAPUR® 102 | EMCOCEL® 90 M | 130 | 0.28 – 0.33 | 0.25 – 0.37 | Medium size standard MCC grade, suited for the majority of directly compressible actives. Combines good flow and high compactibility. |
VIVAPUR® 112 | EMCOCEL® XLM 90 | 130 | 0.30 – 0.36 | 0.25 – 0.37 | Same quality to grades 102/90M, but very low moisture content (< 1.5 %) for processing water-sensitive actives |
VIVAPUR® 302 | EMCOCEL® HD 90 | 130 | 0.35 – 0.50 | 0.38 – 0.50 | Same quality to grade 102/90M, but increased bulk density and improved flow properties. Especially suited for high speed tableting and processing high density actives. |
VIVAPUR® 102 SCG | EMCOCEL® 90 M COARSE | 170/175 | 0.28 – 0.34 | 0.25 – 0.37 | Coarse, DC-grade MCC. |
VIVAPUR® 12 |
| 180 | 0.30 – 0.36 |
| Coarse grade MCC, combines good compactibility and high binding capacity with outstanding flow. Provides good content uniformity at low weight variation – even when used with low concentrations of fine actives. |
VIVAPUR® 14 |
| 170 | 0.32 – 0.40 |
| Same quality to grade 12, but very low moisture content (<1.5 %) for processing water-sensitive actives. |
| EMCOCEL® LP 200 | 220 |
| 0.20 – 0.37 | Coarse grade MCC, combines good compactibility and high binding capacity with outstanding flow. Provides good content uniformity at low weight variation – even when used with low concentrations of fine actives. |
VIVAPUR® 200 |
| 250 | 0.31 – 0.37 |
| Large size MCC grade with excellent flow properties for a variety of direct compression formulations. |
VIVAPUR® 200 XLM |
| 250 | 0.33 – 0.40 |
| Same quality to grades 200/LP200, but very low moisture content (<1.5 %) for processing water-sensitive actives. |
