VIVACOAT® protect E is a white Ready-to-Use enteric coating system based on the globally accepted Metha-crylic Acid-Ethyl Acrylate copolymer (1:1).
VIVACOAT® protect E dissolves at pH values exceeding 5.5. It was developed to protect acid-sensitive APIs against gastric fluids. Likewise, it protects the stomach against irritating actives by delaying drug delivery until the dosage form reaches the small intestine.
The VIVACOAT® protect E system requires no neutralization. This enables an easy one-step reconstitution in water.
Due to the high polymer content of the coating suspension, VIVACOAT® protect E provides short process times.
VIVACOAT® protect E is the ideal solution for delayed release oral dosage forms. Time savings in developement and production are achieved by a simple, fast and robust coating process. Also beneficial are reduced raw material inventory and QC requirements.
We recommend VIVACOAT® PS-1P-041 as sub-coat formulation, if the active ingredient has to be separated from the enteric polymer. For colored tablets, pigmented VIVACOAT® A formulations are ideally suited to be used as a top-coat.
For technical support in lab- and production scale please reach out to JRS Pharma global technical team.
Contact us to obtain your sample of VIVACOAT® protect E.
|Recon Level [%]||Inlet Temp [°C]||Tablet Bed Temp [°C]||Exhaust Temp. [°C]||Total Spray Rate [g/min]||Pan Speed [rpm]|
|Fully Perforated Pan, Batch size 800 g||20||58||30 - 33||35 - 38||2 - 3||7 - 9|
|Conventional Pan, Batch size 2000 - 3000 g||20||n.a.||35 - 38||n.a.||10 - 15||ca. 5|
|Semi Perforated Pan, Batch size 18 - 20 kg||20||50 - 60||32 - 34||46 - 49||55 - 60||3 - 4|
|Fully Perforated Pan, Batch size 18 - 20 kg||20||45 - 55||30 - 33||42 - 44||60 - 70||3 - 4|
|Fully Perforated Pan, Batch size 100 - 120 kg||20||45 - 55||30 - 33||42 - 44||180 - 190||2 - 3|
|Fully Perforated Pan, Batch size 300 - 400 kg||20||45 - 55||30 - 33||42 - 44||700 - 800||1 - 2|
Solid Content 20%