VIVAPUR® MCC Spheres

Microcrystalline Cellulose

VIVAPUR® MCC Spheres consist purely of microcrystalline cellulose, making them extremely robust and chemically inert. They are, therefore, excellently suited as a carrier system. API-layered VIVAPUR® MCC Spheres can be filled into capsules and compacted into tablets.

They possess a tight particle size distribution, allowing for better control and higher batch-to-batch consistency of API release profiles. The particle size uniformity minimizes segregation risks during encapsulation or tableting, permitting greater API content uniformity. Additionally, it is possible to apply different APIs in various concentrations and combine the coated spheres in a single unit dose.

VIVAPUR® MCC Spheres are available in a wide range of particle sizes.

VIVAPUR® MCC Spheres offer:

  • Biologically inert
  • Insoluble in water
  • High degree of sphericity
  • Moisture and heat resistant
  • Adapted for coating and tableting
  • Size < 200 µm available 


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Microcrystalline Cellulose, Ph. Eur., NF, JP, E 460 (i)

Grade

Size

Main Application

(mesh)

(µm)

VIVAPUR® MCC Spheres 100

70 – 140

100 – 200

- Water insoluble carrier

- For organic solvent free API coating

- Small particle sizes available

- High robustness

VIVAPUR® MCC Spheres 200

45 – 70

200 – 355

VIVAPUR® MCC Spheres 350

35 – 45

355 – 500

VIVAPUR® MCC Spheres 500

25 – 35

500 – 710

VIVAPUR® MCC Spheres 700

18 – 25

710 – 1000

VIVAPUR® MCC Spheres 1000

14 – 18

1000 – 1400

 
 
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