The Importance of Binder Selection and its Impact on Tableting Results in Roller Compaction

29. Jan 2016

Roller compaction is the manufacturing method of choice when the physical characteristics of the active do not allow for direct compression and wet granulation causes stability issues due to moisture and heat. In order to achieve the desired granule properties, it is crucial to select binders with good intrinsic compaction properties and reproducible milling results that allow good flowability and high re-compactability during the final tableting step.

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