Lubricants play a vital role in drug tableting applications; however, they can also produce disastrous results if not fully understood and used carefully. If the drug formulation is under-lubricated, the tablet may be difficult to eject from the die; all or parts of the tablet may stick to the die or punch face. Over-lubrication can affect tablet hardness, extend disintegration times, slow drug dissolution, or even prevent tablets from binding.
This webcast will highlight the challenges that formulators face when using certain lubricants in solid-dose drug formulations, will review commonly used lubricants, and will explore a more forgiving and effective alternative for tablet lubrication.
Key Learning Objectives