Sodium Hyaluronate Direct Compression

Most hyaluronic acid supplements for oral intake on the market are available in the form of soft capsules and contain between 50 and 100mg of hyaluronic acid per dose. The aim of this study was to develop high dosage hyaluronic acid tablets by direct compression, which is and easier and more cost-efficient process compared to capsule manufacturing. A formulation composed of the ready-to-use excipient composite PROSOLV® EASYtab and the active ingredient was targeted leading to a simple formulation with only two ingredients.

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