The Use of Sodium Alginate

Extended release tablets are commonly based on partially synthetic cellulose ethers, such as hypromellose (HPMC), hydroxyethyl cellulose (HEC), or hydroxypropyl cellulose (HPC). Alginates offer an interesting, all-natural alternative to these polymers.

The aim of the present study was to investigate the effect of particle size, concentration, and viscosity of various grades of sodium alginate on the performance of modified release tablets.