VIVAPUR® & EMCOCEL®

Microcrystalline Cellulose

Microcrystalline cellulose (MCC) is an odorless, tasteless, porous white powder derived from pharmaceutical grade wood pulp. With a wide range of chemical, technical, and economic benefits, MCC is one of the most widely used binder excipients for tablet formulations.

VIVAPUR® & EMCOCEL® offer:

  • High compactibility
  • Robust tablets with low friability
  • High production yields
  • Cost savings due to reduction in dosage levels
  • Compatibility with most APIs (inert)


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Microcrystalline Cellulose, Ph. Eur., NF, JP, E 460(i), FCC

Air Stream Dried Quality

Spray Dried Quality

Average Particle Size by Laser Diffraction (µm)

Bulk Density (g/mL)

Main Application

VIVAPUR®

EMCOCEL®

VIVAPUR® 105

 

15

max 0.26

 

Very fine grade, which gives a pleasant mouth feeling, masks bitter tastes and supports flavors.

VIVAPUR® 101

EMCOCEL® 50 M

65

0.26 – 0.31

0.25 – 0.37

Fine standard MCC grade, especially suited for wet granulation, roller compaction and spheronization. Very high compactibility.

VIVAPUR® 103

 

65

0.26 – 0.31

 

Same quality as grade 101/50M, but very low moisture content (< 1.5 %) for processing water-sensitive actives.

VIVAPUR® 301

 

65

0.35 – 0.46

 

Same quality as grade 101, but increased bulk density and improved flow properties.

VIVAPUR® 102

EMCOCEL® 90 M

130

0.28 – 0.33

0.25 – 0.37

Medium size standard MCC grade, suited for the majority of directly compressible actives. Combines good flow and high compactibility.

VIVAPUR® 112

EMCOCEL® XLM 90

130

0.30 – 0.36

0.25 – 0.37

Same quality to grades 102/90M, but very low moisture content (< 1.5 %) for processing water-sensitive actives

VIVAPUR® 302

EMCOCEL® HD 90

130

0.35 – 0.50

0.38 – 0.50

Same quality to grade 102/90M, but increased bulk density and improved flow properties. Especially suited for high speed tableting and processing high density actives.

VIVAPUR® 102 SCG

EMCOCEL® 90 M COARSE

170/175

0.28 – 0.34

0.25 – 0.37

Coarse, DC-grade MCC.

VIVAPUR® 12

 

180

0.30 – 0.36

 

Coarse grade MCC, combines good compactibility and high binding capacity with outstanding flow. Provides good content uniformity at low weight variation – even when used with low concentrations of fine actives.

VIVAPUR® 14

 

170

0.32 – 0.40

 

Same quality to grade 12, but very low moisture content (<1.5 %) for processing water-sensitive actives.

 

EMCOCEL® LP 200

220

 

0.20 – 0.37

Coarse grade MCC, combines good compactibility and high binding capacity with outstanding flow. Provides good content uniformity at low weight variation – even when used with low concentrations of fine actives.

VIVAPUR® 200

 

250

0.31 – 0.37

 

Large size MCC grade with excellent flow properties for a variety of direct compression formulations.

VIVAPUR® 200 XLM

 

250

0.33 – 0.40

 

Same quality to grades 200/LP200, but very low moisture content (<1.5 %) for processing water-sensitive actives.

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